The serpent was cursed by God and enmity was placed between the serpent and the woman, and the serpent’s seed and her Seed. The ultimate battle would one day happen between the seed of the serpent and the Seed of the woman:
So the Lord God said to the serpent: “Because you have done this, you are cursed more than all cattle, and more than every beast of the field; on your belly you shall go, and you shall eat dust all the days of your life. And I will put enmity between you and the woman, and between your seed and her Seed; He shall bruise your head, and you shall bruise His heel.”
Genesis 3:14–15 NKJV
This prophecy began to unfold in John 8 as Jesus confronted the religious leaders who hated Him. Jesus identified who their real father was and who their seeds are. It is important to read in context all that Jesus said to grasp the full power of His declaration to the Jews of His day.
So Jesus was saying to those Jews who had believed Him, “If you continue in My word, then you are truly disciples of Mine; and you will know the truth, and the truth will make you free.” They answered Him, “We are Abraham’s descendants and have never yet been enslaved to anyone; how is it that You say, ‘You will become free’?”
Jesus answered them, “Truly, truly, I say to you, everyone who commits sin is the slave of sin. “The slave does not remain in the house forever; the son does remain forever. “So if the Son makes you free, you will be free indeed. “I know that you are Abraham’s descendants; yet you seek to kill Me, because My word has no place in you. I speak the things which I have seen with My Father; therefore you also do the things which you heard from your father.”
They answered and said to Him, “Abraham is our father.” Jesus said to them, “If you are Abraham’s children, do the deeds of Abraham. But as it is, you are seeking to kill Me, a man who has told you the truth, which I heard from God; this Abraham did not do. “You are doing the deeds of your father.” They said to Him, “We were not born of fornication; we have one Father: God.” Jesus said to them, “If God were your Father, you would love Me, for I proceeded forth and have come from God, for I have not even come on My own initiative, but He sent Me. Why do you not understand what I am saying? It is because you cannot hear My word. You are of your father the devil, and you want to do the desires of your father. He was a murderer from the beginning and does not stand in the truth because there is no truth in him. Whenever he speaks a lie, he speaks from his own nature, for he is a liar and the father of lies. But because I speak the truth, you do not believe Me. Which one of you convicts Me of sin? If I speak truth, why do you not believe Me? He who is of God hears the words of God; for this reason you do not hear them, because you are not of God.”